Peanuts to cure a child's peanut allergy? 花生治好孩子的花生過敏？

Peanuts to cure a child's peanut allergy?

Doctors say they are able to treat the deadly allergy by giving children the very thing their bodies reject.  Study results » 

 

Doctors use peanuts to cure children of potentially fatal allergy

 

 

Paris (AFP) - Doctors said Thursday they could treat peanut allergy by feeding children the very thing their bodies reject, so building tolerance that could save a life in case of accidential ingestion.

Small doses of peanut powder taken over several months seemed to induce tolerance in children with the potentially deadly allergy, a research team wrote Wednesday in The Lancet medical journal.

After six months of treatment, dubbed oral immunotherapy or OIT, 84-91 percent of the children in a trial could safely tolerate daily doses of 800 mg (0.03 ounces) of peanut powder -- the equivalent of about five peanuts, wrote the team.
This was 25 times the amount they could tolerate before the therapy, and much larger than any accidental dose is likely to ever be.
"The treatment allowed children with all severities of peanut allergy to eat large quantities of peanuts, well above the levels found in contaminated snacks and meals, freeing them and their parents from the fear of a potentially life threatening allergic reaction," said study leader Andrew Clark from Cambridge University Hospitals.
"The families involved in this study say that it has changed their lives dramatically."
The trial involved 99 allergic children aged seven to sixteen.
One in five of the kids receiving OIT reported "adverse events" -- mostly mild itching of the mouth, the authors said.
They stressed that people should not try the treatment at home as more research was needed.
Peanut allergy affects about one in fifty children and is the most common cause of fatal food allergy reactions, said a press statement. About 10 million people around the world are allergic to peanuts.
Symptoms vary from mild to severe, from swollen lips or shortness of breath to anaphylactic shock, which can be fatal.
While "exceptionally promising", the method remains experimental, Matthew Greenhawt from the University of Michigan Food Allergy Center wrote in a comment also carried by The Lancet.

"It is unknown if OIT can produce lasting tolerance," he wrote.

Article from :　http://news.yahoo.com/using-peanuts-cure-allergy-011535776.html


醫生用花生來治療可能致命的過敏兒童


巴黎（法新社） - 週四醫生說，他們可以把花生過敏餵養的孩子非常的事情他們的身體排斥，從而構建寬容，可以挽救一個生命的情況下，意外攝取。



小劑量的花生粉的接管幾個月似乎誘導免疫耐受的患兒潛在致命過敏，一個研究小組在柳葉刀醫學雜誌上寫道：週三。
治療，被稱為口服免疫治療或OIT的六個月後，在審判的孩子84-91 ％的人能夠安全承受每天服用800毫克（0.03盎司）花生粉 - 約五花生相當於，寫下了隊。
這是25倍，他們的治療之前可容忍的量，並遠遠超過任何意外的較大的劑量可能永遠不會。
“讓孩子花生過敏的所有嚴重性吃大量花生，遠高於污染小吃和餐點中發現的水平，從一個潛在生命的恐懼中解放出來和他們的父母威脅過敏反應的治療， ”研究負責人安德魯說克拉克從劍橋大學醫院。
“參與這項研究的家屬說，它已經極大地改變了他們的生活。 ”
該試驗包括99七至16歲的兒童過敏。
五分之一的人接受OIT孩子們報導的“不良事件” - 口多為輕度瘙癢，作者說。
他們強調，人們不應該嘗試的治療在家中需要更多的研究。
花生過敏影響約在50一兒童節，是致命的食物過敏的反應的最常見原因，說一份新聞聲明。世界各地的大約10萬人對花生過敏。
症狀有所不同從輕微到嚴重，從腫脹的嘴唇或氣短過敏性休克，這可能是致命的。
而“非常有前途” ，該法仍然實驗，馬修Greenhawt密歇根大學食品過敏中心寫在註釋中也由柳葉刀進行。
“這是未知的，如果OIT可產生持久的寬容， ”他寫道。